Maximum Rate of Unitary-Weight, Single-Symbol Decodable STBCs

It is well known that the Space-time Block Codes (STBCs) from Complex orthogonal designs (CODs) are single-symbol decodable/symbol-by-symbol decodable (SSD). The weight matrices of the square CODs are all unitary and obtainable from the unitary matrix representations of Clifford Algebras when the number of transmit antennas $n$ is a power of 2. The rate of the square CODs for $n = 2^a$ has been shown to be $\frac{a+1}{2^a}$ complex symbols per channel use. However, SSD codes having unitary-weight matrices need not be CODs, an example being the Minimum-Decoding-Complexity STBCs from Quasi-Orthogonal Designs. In this paper, an achievable upper bound on the rate of any unitary-weight SSD code is derived to be $\frac{a}{2^{a-1}}$ complex symbols per channel use for $2^a$ antennas, and this upper bound is larger than that of the CODs. By way of code construction, the interrelationship between the weight matrices of unitary-weight SSD codes is studied. Also, the coding gain of all unitary-weight SSD codes is proved to be the same for QAM constellations and conditions that are necessary for unitary-weight SSD codes to achieve full transmit diversity and optimum coding gain are presented.Comment: accepted for publication in the IEEE Transactions on Information Theory, 9 pages, 1 figure, 1 Tabl

Assessment of the biomechanical properties of the cornea with the ocular response analyzer in normal and keratoconic eyes

PURPOSE. To compare hysteresis, a novel measure of ocular rigidity (viscoelasticity) in normal and keratoconic eyes. METHODS. The study consisted of 207 normal and 93 keratoconic eyes. Eyes were diagnosed as keratoconic based on clinical examination and corneal topography. The hysteresis was measured by the Ocular Response Analyzer (ORA; Reichert Ophthalmic Instruments, Buffalo, NY). The data were recorded by Generation 3 software for the ORA. Central corneal thickness (CCT) was measured with a handheld ultrasonic pachymeter in the midpupillary axis. RESULTS. The mean hysteresis was 10.7 ± 2.0 (SD) mm Hg (range, 6.1-17.6) in normal eyes compared with 9.6 ± 2.2 mm Hg (range, 4.7-16.7) in keratoconic eyes. The difference was statistically significant (P < 0.0001, unpaired t-test). Mean CCT in the normal and keratoconic eyes was 545.0 ± 36.4 μm (range, 471-650) and 491.8 ± 54.7 μm (range, 341-611), respectively; the difference was significant (P < 0.0001, unpaired t-test). CONCLUSIONS. Hysteresis was significantly higher in normal than in keratoconic eyes. It may be a useful measurement in addition to CCT, when assessing ocular rigidity, and may be of particular importance when trying to correct intraocular measurements for increased or decreased ocular rigidity. Long-term studies of change in hysteresis may provide information on the progression of keratoconus

Minimum-Decoding-Complexity, Maximum-rate Space-Time Block Codes from Clifford Algebras

It is well known that Alamouti code and, in general, Space-time Block Codes (STBCs) from Complex Orthogonal Designs (CODs) are Single-symbol decodable/symbol-by-symbol Decodable (SSD) and are obtainable from unitary matrix representations of Clifford algebras. However, SSD codes are obtainable from designs that are not CODs. Recently, two such classes of SSD codes have been studied: (i) Coordinate Interleaved Orthogonal Designs (CIODs) and (ii) Minimum-decoding-complexity (MDC) STBCs from Quasi-ODs (QODs). In this paper, we obtain SSD codes with unitary weight matrices (but not CODs) from matrix representations of Clifford algebras. Moreover, we derive an upper bound on the rate of SSD codes with unitary weight matrices and show that our codes meet this bound. Also, we present conditions on the signal sets which ensure full-diversity and give expressions for the coding gain

Evaluation of bio-asphalt binders modified with biochar: a pyrolysis by-product of Mesua ferrea seed cover waste

With growing global concerns related to energy security and sustainability, interest in bio-fuels has increased significantly. Production of biofuel mostly begins with pyrolysis, a process that converts the biomass to liquid biooil, solid biochar and gases. A large amount of carbonaceous biochar is generated as a by-product during the pyrolysis. However, no major effort has been made in the past decade to utilize the biochar in pavement applications, especially as a bio-modifier to asphalt binders. In this study, an attempt was made to evaluate the carbonaceous biochar, obtained during bio-fuel production through pyrolysis of Mesua ferrea seed cover waste, as an asphalt modifier/extender to obtain bio-asphalts. Physical and chemical characterizations of biochar were carried out using scanning electron microscopy, Fourier transform infrared spectroscopy and energy dispersive X-ray analysis. This was followed by rheological characterization of asphalt binders (from two sources) modified with various concentrations of biochar (0, 5, 10, 15, and 20% by weight of binder). Flow behaviour, permanent deformation, and fatigue characteristics of bio-asphalts were evaluated and compared with control binders (no biochar). Aging susceptibility of biochar modified binders was also evaluated and compared for biochar contents and binder sources. Permanent deformation behaviour evaluated through multiple stress creep and recovery (MSCR) test indicated that the use of biochar improved the rutting resistance of binders. Improved binder performance against the effects of aging and deformation with the use of biochar makes it a promising asphalt modifier, especially for the warm tropical climatic conditions prevalent in India

Autonomy Operating System for UAVs: Pilot-in-a-Box

The Autonomy Operating System (AOS) is an open flight software platform with Artificial Intelligence for smart UAVs. It is built to be extendable with new apps, similar to smartphones, to enable an expanding set of missions and capabilities. AOS has as its foundations NASAs core flight executive and core flight software (cFEcFS). Pilot-in-a-Box (PIB) is an expanding collection of interacting AOS apps that provide the knowledge and intelligence onboard a UAV to safely and autonomously fly in the National Air Space, eventually without a remote human ground crew. Longer-term, the goal of PIB is to provide the capability for pilotless air vehicles such as air taxis that will be key for new transportation concepts such as mobility-on-demand. PIB provides the procedural knowledge, situational awareness, and anticipatory planning (thinking ahead of the plane) that comprises pilot competencies. These competencies together with a natural language interface will enable Pilot-in-a-Box to dialogue directly with Air Traffic Management from takeoff through landing. This paper describes the overall AOS architecture, Artificial Intelligence reasoning engines, Pilot-in-a-box competencies, and selected experimental flight tests to date

Recreational marathon running does not cause exercise-induced left ventricular hypertrabeculation.

BACKGROUND: Marathon running in novices represents a natural experiment of short-term cardiovascular remodeling in response to running training. We examine whether this stimulus can produce exercise-induced left ventricular (LV) trabeculation. METHODS: Sixty-eight novice marathon runners aged 29.5 ± 3.2 years had indices of LV trabeculation measured by echocardiography and cardiac magnetic resonance imaging 6 months before and 2 weeks after the 2016 London Marathon race, in a prospective longitudinal study. RESULTS: After 17 weeks unsupervised marathon training, indices of LV trabeculation were essentially unchanged. Despite satisfactory inter-observer agreement in most methods of trabeculation measurement, criteria defining abnormally hypertrabeculated cases were discordant with each other. LV hypertrabeculation was a frequent finding in young, healthy individuals with no subject demonstrating clear evidence of a cardiomyopathy. CONCLUSION: Training for a first marathon does not induce LV trabeculation. It remains unclear whether prolonged, high-dose exercise can create de novo trabeculation or expose concealed trabeculation. Applying cut off values from published LV noncompaction cardiomyopathy criteria to young, healthy individuals risks over-diagnosis

The Wolbachia Genome of Brugia malayi: Endosymbiont Evolution within a Human Pathogenic Nematode

Complete genome DNA sequence and analysis is presented for Wolbachia, the obligate alpha-proteobacterial endosymbiont required for fertility and survival of the human filarial parasitic nematode Brugia malayi. Although, quantitatively, the genome is even more degraded than those of closely related Rickettsia species, Wolbachia has retained more intact metabolic pathways. The ability to provide riboflavin, flavin adenine dinucleotide, heme, and nucleotides is likely to be Wolbachia's principal contribution to the mutualistic relationship, whereas the host nematode likely supplies amino acids required for Wolbachia growth. Genome comparison of the Wolbachia endosymbiont of B. malayi (wBm) with the Wolbachia endosymbiont of Drosophila melanogaster (wMel) shows that they share similar metabolic trends, although their genomes show a high degree of genome shuffling. In contrast to wMel, wBm contains no prophage and has a reduced level of repeated DNA. Both Wolbachia have lost a considerable number of membrane biogenesis genes that apparently make them unable to synthesize lipid A, the usual component of proteobacterial membranes. However, differences in their peptidoglycan structures may reflect the mutualistic lifestyle of wBm in contrast to the parasitic lifestyle of wMel. The smaller genome size of wBm, relative to wMel, may reflect the loss of genes required for infecting host cells and avoiding host defense systems. Analysis of this first sequenced endosymbiont genome from a filarial nematode provides insight into endosymbiont evolution and additionally provides new potential targets for elimination of cutaneous and lymphatic human filarial disease

Harnessing the probiotic properties and immunomodulatory effects of fermented food-derived Limosilactobacillus fermentum strains: implications for environmental enteropathy

IntroductionEnvironmental enteropathy (EE), a chronic small intestine disease characterized by gut inflammation, is widely prevalent in low-income countries and is hypothesized to be caused by continuous exposure to fecal contamination. Targeted nutritional interventions using potential probiotic strains from fermented foods can be an effective strategy to inhibit enteric pathogens and prevent chronic gut inflammation.MethodsWe isolated potential strains from fermented rice water and lemon pickle and investigated their cell surface properties, antagonistic properties, adhesion to HT-29 cells, and inhibition of pathogen adherence to HT-29 cells. Bacteriocin-like inhibitory substances (BLIS) were purified, and in vivo, survival studies in Caenorhabditis elegans infected with Salmonella enterica MW116733 were performed. We further checked the expression pattern of pro and anti-inflammatory cytokines (IL-6, IL8, and IL-10) in HT-29 cells supplemented with strains.ResultsThe strains isolated from rice water (RS) and lemon pickle (T1) were identified as Limosilactobacillus fermentum MN410703 and MN410702, respectively. Strains showed probiotic properties like tolerance to low pH (pH 3.0), bile salts up to 0.5%, simulated gastric juice at low pH, and binding to extracellular matrix molecules. Auto-aggregation of T1 was in the range of 85% and significantly co-aggregated with Klebsiella pneumoniae, S. enterica, and Escherichia coli at 48, 79, and 65%, respectively. Both strains had a higher binding affinity to gelatin and heparin compared to Bacillus clausii. Susceptibility to most aminoglycoside, cephalosporin, and macrolide classes of antibiotics was also observed. RS showed BLIS activity against K. pneumoniae, S. aureus, and S. enterica at 60, 48, and 30%, respectively, and the protective effects of BLIS from RS in the C. elegans infection model demonstrated a 70% survival rate of the worms infected with S. enterica. RS and T1 demonstrated binding efficiency to HT-29 cell lines in the 38–46% range, and both strains inhibited the adhesion of E. coli MDR and S. enterica. Upregulation of IL-6 and IL-10 and the downregulation of IL-8 were observed when HT-29 cells were treated with RS, indicating the immunomodulatory effects of the strain.DiscussionThe potential strains identified could effectively inhibit enteric pathogens and prevent environmental enteropathy